2026-04-12T07:35:48Z https://www.fdr.uni-hamburg.de/oai2d

oai:fdr.uni-hamburg.de:12047 2023-05-22T07:35:49Z user-sfb936 user-uhh

Ossandón, José P. 2023-05-17 Code for the statistical analyses, figures, and the anonymized, pre-processed spectral data from the publication: "The development of oscillatory and aperiodic resting state activity is linked to a sensitive period in humans" published in Neuroimage https://doi.org/10.1016/j.neuroimage.2023.120171 See README file for details. https://www.fdr.uni-hamburg.de/record/12047 10.25592/uhhfdm.12047 oai:fdr.uni-hamburg.de:12047 doi:10.1016/j.neuroimage.2023.120171 doi:10.25592/uhhfdm.12046 info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/legalcode EEG resting state activity dataset from congenitally blind and sight-recovery individuals info:eu-repo/semantics/other dataset

oai:fdr.uni-hamburg.de:12692 2023-07-10T07:19:36Z user-sfb936 user-uke user-uhh

Haaf, Moritz 2023-07-10 The dataset consists of single trial EEG data that was recorded from 24 participants during the performance of an auditory choice reaction task. Each participant completed the recording on separate days during the infusion of placebo (0-0) or sub-anesthetic ketamine (0-1). Type of data: EEG single trial ASCII data (64 channels, extended 10-20 system) 1000 Hz sampling rate What is the question/hypothesis behind the dataset? To test whether ketamine reduces the auditory evoked gamma response Which paradigm has been used? Cognitively demanding auditory choice reaction task (3 tones, 2 answers) S1 (800 Hz) and S3 (1200 Hz) markers code for target tone presentation S2 (1000 Hz) is the marker coding for the non-target tone S101 (for S1) and S103 (for S 3) are the response markers Which methods have been applied so far to analyse the dataset? Time-frequency analysis (focus on 40 Hz), phase locking factor, sLORETA source localization The dataset is described in more detail in the following publication: https://doi.org/10.1016/j.neuroimage.2022.119004 https://www.fdr.uni-hamburg.de/record/12692 10.25592/uhhfdm.12692 oai:fdr.uni-hamburg.de:12692 eng doi:10.25592/uhhfdm.12691 info:eu-repo/semantics/restrictedAccess The ketamine model of schizophrenia: EEG single trial data during an auditory choice reaction task info:eu-repo/semantics/other dataset

oai:fdr.uni-hamburg.de:12972 2023-07-23T19:53:50Z user-sfb936 user-uhh

Forlim, Caroline G Fischer, Djo Becker, Maxi Gallinat, Jürgen Kühn, Simone 2023-07-20 Data (brain, behaviour, blood and glutamate) and code in R for statistical analysis of a longitudinal training study in which patients and healthy controls were randomly assigned to train with a 3D or 2D platformer game or read an E-book for 8 weeks, 30 minutes a day. Groups: patients with schizophrenia or schizoaffective disorder (N=59) and healthy participants (N=76). Brain measures: functional and structural measures, namely, functional connectivity and brain volume: overall grey matter volume, grey matter volume per ROI, functional connectivity between ROIs of the prefrontal-hippocampal network. Scores: the positive and negative syndrome scale (PANSS), perceived mental health recovery (RAS), MATRICS consensus cognitive battery, tunnel task, blood biomarkers (BDNF), glutamate, Olanzapin equivalent, gender, age, education, game difficulty and game fun. https://www.fdr.uni-hamburg.de/record/12972 10.25592/uhhfdm.12972 oai:fdr.uni-hamburg.de:12972 doi:10.25592/uhhfdm.12971 info:eu-repo/semantics/restrictedAccess Augmentation of neuronal network plasticity in schizophrenia info:eu-repo/semantics/other dataset

oai:fdr.uni-hamburg.de:11175 2024-02-21T13:03:20Z user-sfb936 user-uhh

Stange, Liesa 2022-12-15 Preprocessed data, behavioral data, EEG analysis code, behavioral analysis code, 3 functions for plottin ERPs https://www.fdr.uni-hamburg.de/record/11175 10.25592/uhhfdm.11175 oai:fdr.uni-hamburg.de:11175 doi:10.25592/uhhfdm.11174 info:eu-repo/semantics/restrictedAccess Omission Data info:eu-repo/semantics/other dataset

oai:fdr.uni-hamburg.de:12378 2023-06-05T11:17:58Z user-uhh user-sfb936

Jonas Misselhorn Bettina C. Schwab Till R. Schneider Uwe Friese Andreas K. Engel 2023-05-30 Raw EEG and behavioral data measured at the Institute of Neurophysiology and Pathophysiology, University Medical Center Hamburg-Eppendorf, Germany, in 2015. Results were published in: Misselhorn J, Friese U, Engel AK. Frontal and parietal alpha oscillations reflect attentional modulation of cross-modal matching. Sci Rep. 2019 Mar 22;9(1):5030. doi: 10.1038/s41598-019-41636-w. PMID: 30903012; PMCID: PMC6430816. Misselhorn J, Schwab BC, Schneider TR, Engel AK. Synchronization of Sensory Gamma Oscillations Promotes Multisensory Communication. eNeuro. 2019 Oct 31;6(5):ENEURO.0101-19.2019. doi: 10.1523/ENEURO.0101-19.2019. PMID: 31601635; PMCID: PMC6873160. https://www.fdr.uni-hamburg.de/record/12378 10.25592/uhhfdm.12378 oai:fdr.uni-hamburg.de:12378 eng doi:10.25592/uhhfdm.12377 info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/legalcode 128 Channel EEG Multisensory integration Crossmodal attention Trimodal multisensory matching – EEG and behavioral data info:eu-repo/semantics/other dataset

oai:fdr.uni-hamburg.de:12576 2023-06-23T13:22:03Z user-uhh user-sfb936 user-uke

Cheng, Bastian 2023-06-21 Longitudinal, structural brain connectome dataset derived by DWI and probabilistic tractography. Details provided in the methods file. Patients with first ever supratentorial stroke and upper extremity deficits were included. Timepoints of examinations: 3-5 days after stroke, 1 month, 3 month and 1 year. Related Publications: https://doi.org/10.1093/braincomms/fcz020 10.1177/0271678X19831583 https://www.fdr.uni-hamburg.de/record/12576 10.25592/uhhfdm.12576 oai:fdr.uni-hamburg.de:12576 doi:10.25592/uhhfdm.12575 info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/legalcode Longititudinal acute stroke study: structural brain connectomes info:eu-repo/semantics/other dataset

oai:fdr.uni-hamburg.de:13395 2023-09-26T07:33:31Z user-sfb936 user-uhh

Formozov, Andrey Chini, Mattia Dieter, Alexander Yang, Wei Pöpplau, Jastyn A. Hanganu-Opatz, Ileana L. Wiegert, Simon 2022-01-25 Large-scale, annotated collection of 2-photon calcium imaging data in CA1 of the murine hippocampus under three distinct anesthetics (Isoflurane, Keta/Xyl and MMF), during natural sleep, and during wakefulness. Direct link to the published dataset: https://doi.gin.g-node.org/10.12751/g-node.s549qk/ https://www.fdr.uni-hamburg.de/record/13395 10.12751/g-node.s549qk oai:fdr.uni-hamburg.de:13395 info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/legalcode Neuroscience Anesthesia Anaesthesia Sleep Recovery Hippocampus CA1 Pyramidal neurons Calcium imaging data Pupillometry Calcium imaging of hippocampal activity under anesthesia and natural sleep in mice info:eu-repo/semantics/other dataset

oai:fdr.uni-hamburg.de:12376 2023-06-05T11:18:04Z user-uhh user-sfb936

Jonas Misselhorn Jonathan Daume Andreas K. Engel Uwe Friese 2023-05-30 Raw behavioral data measured at the Institute of Neurophysiology and Pathophysiology, University Medical Center Hamburg-Eppendorf, Germany, in 2015. Results were published as Misselhorn J, Daume J, Engel AK, Friese U. A matter of attention: Crossmodal congruence enhances and impairs performance in a novel trimodal matching paradigm. Neuropsychologia. 2016 Jul 29;88:113-122. doi: 10.1016/j.neuropsychologia.2015.07.022. Epub 2015 Jul 21. PMID: 26209356. https://www.fdr.uni-hamburg.de/record/12376 10.25592/uhhfdm.12376 oai:fdr.uni-hamburg.de:12376 eng doi:10.25592/uhhfdm.12375 info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/legalcode Behavioral data Multisensory integration Crossmodal attention Trimodal multisensory matching – behavioral data info:eu-repo/semantics/other dataset

oai:fdr.uni-hamburg.de:12696 2023-09-18T08:56:44Z user-sfb936 user-uhh

Calder-Travis*, Joshua van den Brink*, Ruud Thawani, Saanchi Schwabe, Lars Donner, Tobias 2023-07-06 info:eu-repo/date/embargoEnd/2029-07-05 *Joint first authors Behavioural, MEG and eye tracking data from an experiment exploring how humans achieve rapid switches between arbitrary stimulus to response mappings. The experimental procedure is described in one of the preregistrations associated with the study (https://osf.io/hnwfr). https://www.fdr.uni-hamburg.de/record/12696 10.25592/uhhfdm.12696 oai:fdr.uni-hamburg.de:12696 eng url:https://osf.io/hnwfr url:https://osf.io/h4x5s doi:10.25592/uhhfdm.12695 info:eu-repo/semantics/embargoedAccess https://creativecommons.org/licenses/by/4.0/legalcode Exploring rapidly changing sensory-motor mappings in behaviour and MEG info:eu-repo/semantics/other dataset

oai:fdr.uni-hamburg.de:13397 2023-09-26T07:33:30Z user-sfb936 user-uhh

Basedau, Hauke Sturm, Lisa-Marie Mehnert, Jan Peng, Kuan-Po Schellong, Marlene May, Arne 2022-06-01 Background: Monoclonal antibodies (mAbs) against calcitonin gene-related peptides (CGRP) are novel treatments for migraine prevention. Based on a previous functional imaging study which investigated the CGRP receptor mAb (erenumab), we hypothesized that (i) the CGRP ligand mAb galcanezumab would alter central trigeminal pain processing; (ii) responders to galcanezumab treatment would show specific hypothalamic modulation in contrast to non-responders; and (iii) the ligand and the receptor antibody differ in brain responses. Methods: Using an established trigeminal nociceptive functional magnetic imaging paradigm, 26 migraine patients were subsequently scanned twice: before and 2–3 weeks after administration of galcanezumab. Results: We found that galcanezumab decreases hypothalamic activation in all patients and that the reduction was stronger in responders than in non-responders. Contrasting erenumab and galcanezumab showed that both antibodies activate a distinct network. We also found that pre-treatment activity of the spinal trigeminal nucleus (STN) and coupling between the STN and the hypothalamus covariates with the response to galcanezumab. Conclusions: These data suggest that despite relative impermeability of the blood-brain barrier for CGRP mAb, mAb treatment induces certain and highly specific brain effects which may be part of the mechanism of their efficacy in migraine treatment. Funding: This work was supported by the German Ministry of Education and Research (BMBF) of ERA-Net Neuron under the project code BIOMIGA (01EW2002 to AM) and by the German Research Foundation (SFB936-178316478-A5 to AM). The funding sources did not influence study conduction in any way. Clinical trial number: The basic science study was preregistered in the Open Science Framework (https://osf.io/m2rc6). Direct link to the published dataset: https://datadryad.org/stash/dataset/doi:10.5061/dryad.w3r2280t2 https://www.fdr.uni-hamburg.de/record/13397 10.5061/dryad.w3r2280t2 oai:fdr.uni-hamburg.de:13397 eng info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/legalcode Hypothalamus Migraine Other medical sciences CGRP antibodies functional imaging General Biochemistry, Genetics and Molecular Biology General Immunology and Microbiology General Medicine General Neuroscience pathophysiology Migraine monoclonal antibodies against CGRP change brain activity depending on ligand or receptor target – an fMRI study info:eu-repo/semantics/other dataset

oai:fdr.uni-hamburg.de:13399 2023-09-26T07:33:29Z user-sfb936 user-uhh

Verrel, Julius Münchau, Alexander Klein, Christine 2023-09-19 Time estimation task, performed by DRD patients (ON/OFF L-Dopa) as well as HC (Session 1/2). Experimental data, clinical data and analysis scripts (Matlab, R). Direct link to the published dataset: https://osf.io/j4xqg/ https://www.fdr.uni-hamburg.de/record/13399 10.25592/uhhfdm.13399 oai:fdr.uni-hamburg.de:13399 eng doi:10.25592/uhhfdm.13398 info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/legalcode Time estimation and arousal responses in dopa-responsive dystonia info:eu-repo/semantics/other dataset

oai:fdr.uni-hamburg.de:12550 2023-06-16T08:35:17Z user-uhh user-sfb936

Galindo-Leon, Edgar Stitt, Iain Pieper, Florian Stieglitz, Thomas Engler, Gerhard Engel, Andreas K. 2019-04-10 Epicortical LFP data of auditory and visual responses in anesthetized ferrets (isoflurane) were recorded with a custom ECoG array of 64 electrodes at the Institute of Neurophysiology and Pathophysiology, UKE. The results were published in "Context-specific modulation of intrinsic coupling modes shapes multisensory processing", Galindo-Leon et al., Sci. Adv. 2019. https://www.fdr.uni-hamburg.de/record/12550 10.25592/uhhfdm.12550 oai:fdr.uni-hamburg.de:12550 eng doi:10.25592/uhhfdm.12549 info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/legalcode LFP, ECoG, Ferret Audiovisual integration in anesthetized ferret - ECoG data. info:eu-repo/semantics/other dataset

oai:fdr.uni-hamburg.de:12552 2023-06-16T08:34:55Z user-uhh user-sfb936

Fischer, Felix Pieper, Florian Galindo-Leon, Edgar Engler, Gerhard Hilgetag, Claus Engel, Andreas K. 2023-06-15 Resting state recordings of LFP signals using an ECoG array of 64 channels in anaesthetised ferrets. The activity was recorded varying the levels of isuflorane (13 levels in total). Results are published in Cerebral Cortex (F. Fischer et al, "Intrinsic Functional Connectivity Resembles Cortical Architecture at Various Levels of Isoflurane Anesthesia", 2018) https://www.fdr.uni-hamburg.de/record/12552 10.25592/uhhfdm.12552 oai:fdr.uni-hamburg.de:12552 eng doi:10.25592/uhhfdm.12551 info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/legalcode ECoG, Isoflurane, Ferret, cortex Cortical Architecture at Various Levels of Isoflurane Anesthesia info:eu-repo/semantics/other dataset

oai:fdr.uni-hamburg.de:12762 2023-07-11T12:09:40Z user-uhh user-uke user-sfb936

Martin A. Horn Alessandro Gulberti Ute Hidding Christian Gerloff Wolfgang Hamel Christian K. E. Moll Monika Pötter-Nerger 2023-07-11 Background: The Parkinsonian [i.e., Parkinson's disease (PD)] gait disorder represents a therapeutical challenge with residual symptoms despite the use of deep brain stimulation of the subthalamic nucleus (STN DBS) and medical and rehabilitative strategies. The aim of this study was to assess the effect of different DBS modes as combined stimulation of the STN and substantia nigra (STN+SN DBS) and environmental rehabilitative factors as footwear on gait kinematics. Methods: This single-center, randomized, double-blind, crossover clinical trial assessed shod and unshod gait in patients with PD with medication in different DBS conditions (i.e., STIM OFF, STN DBS, and STN+SN DBS) during different gait tasks (i.e., normal gait, fast gait, and gait during dual task) and compared gait characteristics to healthy controls. Notably, 15 patients participated in the study, and 11 patients were analyzed after a dropout of four patients due to DBS-induced side effects. Results: Gait was modulated by both factors, namely, footwear and DBS mode, in patients with PD. Footwear impacted gait characteristics in patients with PD similarly to controls with longer step length, lower cadence, and shorter single-support time. Interestingly, DBS exerted specific effects depending on gait tasks with increased cognitive load. STN+SN DBS was the most efficient DBS mode compared to STIM OFF and STN DBS with intense effects as step length increment during dual task. Conclusion: The PD gait disorder is a multifactorial symptom, impacted by environmental factors as footwear and modulated by DBS. DBS effects on gait were specific depending on the gait task, with the most obvious effects with STN+SN DBS during gait with increased cognitive load. https://www.fdr.uni-hamburg.de/record/12762 10.25592/uhhfdm.12762 oai:fdr.uni-hamburg.de:12762 eng url:https://www.frontiersin.org/articles/10.3389/fnhum.2021.751242/full doi:10.25592/uhhfdm.12761 info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/legalcode Frontiers in Human Neuroscience 15 barefoot, shoes, gait, deep brain stimulation, subthalamic nucleus, substantia nigra, Parkinson's disease Comparison of Shod and Unshod Gait in Patients With Parkinson's Disease With Subthalamic and Nigral Stimulation info:eu-repo/semantics/other dataset

oai:fdr.uni-hamburg.de:13401 2023-09-26T08:45:40Z user-sfb936 user-uhh

Hilgetag, Claus Büchel, Christine Ritter, Petra Morellini, Fabio Oertner, Thomas Gerloff Thomalla Ritter 2023-09-26 Subproject A1 Database Ferretome - Ferret brain connectivity database A database of anatomic connections and architectonic features of the ferret brain. https://icns-nas1.uke.uni-hamburg.de:4430/ferretome/main/index.php Subproject A6 Dataset Generic acquisition protocol for quantitative MRI of the spinal cord Identifier: DOI 10.17605/OSF.IO/TT4Z9 Description: Optimized and standardized MRI acquisition protocols for the spinal cord, compatible with Siemens, GE and Philips scanners. https://osf.io/tt4z9/ Subproject B7 Dataset attached to the article: ΔFosB accumulation in hippocampal granule cells drives cFos pattern separation during spatial learning https://www.nature.com/articles/s41467-022-33947-w#additional-information Subproject C1, C2, C9 Database EBRAINS Access only with registration under https://www.ebrains.eu/page/sign-up https://search.kg.ebrains.eu/live/814cc815-8b00-47e1-af09-7dd2d8560abd Subproject C9 Scripts This module currently provides a solution to interface between TVB and NEST spiking networks for multiscale co-simulations. https://github.com/the-virtual-brain/tvb-multiscale/tree/Meier_etal_ExpNeur2021 https://www.fdr.uni-hamburg.de/record/13401 10.25592/uhhfdm.13401 oai:fdr.uni-hamburg.de:13401 eng doi:10.25592/uhhfdm.13400 info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/legalcode MRI spinal cord ΔFosB EBRAINS TVB and NEST spiking Ferretome - Ferret brain connectivity database Documentation of other research data and databases used info:eu-repo/semantics/other other

oai:fdr.uni-hamburg.de:13393 2023-09-26T07:33:32Z user-sfb936 user-uhh

Formozov, Andrey Chini, Mattia Dieter, Alexander Yang, Wei Pöpplau, Jastyn A. Hanganu-Opatz, Ileana L. Wiegert, J. Simon 2022-01-25 Large-scale, annotated collection of 2-photon calcium imaging data and electrophysiological recordings in CA1 of the murine hippocampus under three distinct anesthetics (Isoflurane, Keta/Xyl and MMF), during natural sleep, and during wakefulness. Direct link to the published dataset: https://doi.gin.g-node.org/10.12751/g-node.lkx6kk/ https://www.fdr.uni-hamburg.de/record/13393 10.12751/g-node.lkx6kk oai:fdr.uni-hamburg.de:13393 eng info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/legalcode Neuroscience Anesthesia Anaesthesia Sleep Recovery Hippocampus CA1 Pyramidal neurons Calcium imaging data Electrophysiological recordings Pupillometry EMG data Calcium imaging and electrophysiology of hippocampal activity under anesthesia and natural sleep in mice info:eu-repo/semantics/other dataset

oai:fdr.uni-hamburg.de:13391 2023-09-25T14:38:14Z user-sfb936 user-uhh

Chini, Mattia Pöpplau, Jastyn A. Lindemann, Christoph Carol-Perdiguer, Laura Hnida, Marilena Oberländer, Victoria Xu, Xiaxia Ahlbeck, Joachim Bitzendorfer, Sebastian H. Mulert, Christoph Hanganu-Opatz, Ileana L. 2019-11-13 Electrophysiological recordings from prefrontal cortex of 60 not-anesthetized postnatal day 4-10 mice: - 13 P4-6 control mice - 13 P4-6 dual-hit GE mice - 16 P8-10 control mice - 18 P8-10 dual-hit GE mice. Direct link to the published dataset: https://doi.gin.g-node.org/10.12751/g-node.f3e198/ https://www.fdr.uni-hamburg.de/record/13391 10.12751/g-node.f3e198 oai:fdr.uni-hamburg.de:13391 eng info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/legalcode Neuroscience Electrophysiology Cognitive impairment Neonatal Mice Prefrontal cortex Neurodevelopment Mental disorders LFP SUA Not-anesthetized ephys data associated with the paper *Resolving and rescuing developmental miswiring in a mouse model of cognitive impairment* info:eu-repo/semantics/other dataset