Dataset Open Access
Integrative omics and phase IIa clinical trial identify TNF as key node in autoimmune hepatitis
Xu, Yang; Weltzsch, Jan Philipp; Kilian, Christoph; Steglich, Babett; Herkel, Johannes; Adlung, Lorenz; Schramm, Christoph; Gagliani, Nicola; Lohse, Ansgar Wilhelm
Processed single cell sequencing data from Xu, Weltzsch, Kilian et al., J Hepat 2026 . This repository contains an anonymized set of Seurat objects of the human single cell sequencing data and spatial transcriptomics, as well as DEG lists. Human single cell count matrices and spatial transcriptomics data are available under restricted access due to the data privacy. Access can be obtained by contacting Prof. Ansgar Lohse (a.lohse@uke.de), and signing a data transfer agreement.
Files
(1.6 GB)
| Name | Size | |
|---|---|---|
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DEG_Tables_top30.xlsx
md5:a8f6e4acd3b5e81d117599422359afee |
118.0 kB | Download |
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DTA_UKE_AIH.docx
md5:6d163f14c4743bf599063d1b1e909205 |
28.8 kB | Download |
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ED_Fig4C_PBMC_Liver_Tcells.rds
md5:ca574db8e395a719bdc4a5af8427d8fc |
280.1 MB | Download |
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ED_Fig6B_Xenium_AIH.rds
md5:0fcb11568d178e6bccedd48294e1d7d4 |
144.0 MB | Download |
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ED_Fig6C_Xenium_Control.rds
md5:0ccd30865b9ac9f02e963d6a1dbcedd1 |
25.7 MB | Download |
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Fig2BC_SCS_SNS_AIH_atlas.rds
md5:9d024d29a917a59276d1802d41578392 |
728.8 MB | Download |
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Fig2D_SCS_SNS_CD4_Tcells.rds
md5:70c08ec3828c35fcf9defd4717183875 |
35.1 MB | Download |
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Fig2E_SCS_SNS_CD8_Tcells.rds
md5:76dc2ec5790f633c820966596e070c50 |
120.8 MB | Download |
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Fig2F_SNS_Hepatocytes.rds
md5:f3fb081f1ee3087f52f4f089f3c139fa |
258.4 MB | Download |
- Publication date:
- August 13, 2026
- DOI:
-
- Communities:
- License (for files):
- Creative Commons Attribution 4.0 International